Invasive Fungal Rhinosinusitis (IFS)

In immunocompetent patients, IFS typically presents with nasal congestion and periorbital discomfort.  In immunocompromised patients however, IFS often presents with masses, proptosis and bony erosion, typically with rapid progression.

Acute invasive fungal rhinosinusitis (AIFR) is a rare but frequently fatal infection that occurs primarily in immunocompromised individuals and diabetics.i It is characterized by fungal invasion into the mucosa and submucosal structures of the paranasal sinuses with frequent extension into adjacent structures, including the paranasal soft tissues, orbit and cranial vault.  Short term mortality has been reported to range from 20-68% across studies.[i]i

Surgery is the primary approach to IFS. Photodisinfection is a potent anti-fungal therapy that can help to address the IFS patient population with its minimally invasive advantages. 


ii Monroe Marcus M. et al, Invasive Fungal Rhinosinusitis: A 15 Year Experience with 29 Patients. The Laryngoscope 2013 Feb.


Sinuwaveis only available in Canada 

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